Can online therapy lift depression in spinal cord injury patients?

NCT ID NCT06233656

Ongoing Symptom relief Sponsor: University of South Florida Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether 8 weeks of acceptance and commitment therapy (ACT) delivered via Zoom can help reduce depression in people with spinal cord injuries. 140 participants with mild or worse depressive symptoms will be randomly assigned to either ACT or a wait-list that continues usual care. The goal is to see if ACT improves mood and quality of life compared to no additional treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: acceptance and commitment therapy (ACT)
What this could lead to: If it works, this could provide an effective, accessible way to reduce depression and improve quality of life for people with spinal cord injuries.
What could go wrong: This is a relatively small, early-stage trial with a wait-list control, so results may not be definitive. The therapy requires active participation and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION SPINAL CORD INJURIES

Contacts and locations

Locations

University of South Florida

Tampa, Florida, 33612, United States

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