Promising early results for Two-Drug combo in blood cancer patients

NCT ID NCT02296918

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This early-phase study tested a combination of two drugs, acalabrutinib and obinutuzumab, in 69 people with chronic lymphocytic leukemia (CLL) or related blood cancers. The goal was to see if the combination was safe and could shrink or eliminate cancer. Participants included those whose cancer had returned after prior treatment and those who had not yet been treated. The study found that the combination was generally safe and showed signs of effectiveness, but ongoing treatment is needed to control the disease.

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Contacts and locations

Locations

  • Research Site

    Columbus, Ohio, 43210, United States

Conditions

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