New drug shrinks tumors in hard-to-treat blood cancers

NCT ID NCT02337829

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tested a drug called acalabrutinib in 48 adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who had a high-risk genetic change (deletion 17p). The goal was to see how well the drug shrank tumors. Results showed that many patients had a partial or complete response, meaning their cancer got smaller or disappeared for a time. This is a disease-control treatment, not a cure, as patients may need ongoing therapy.

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Contacts and locations

Locations

  • Research Site

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.