Knee replacement showdown: which design lets you move best?
NCT ID NCT04855864
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at three different knee replacement designs: one that keeps the ACL, one that substitutes for it, and one that sacrifices it. Researchers want to see which design gives the best function, pain relief, and satisfaction in 75 people with severe knee arthritis. Participants will be followed with questionnaires, motion analysis, and X-rays to compare outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- knee replacement designs (bicruciate retaining, bicruciate stabilized, posterior stabilized)
- What this could lead to
- If successful, this could help surgeons choose the best knee replacement design for younger, active patients, leading to better function and satisfaction.
- What could go wrong
- This is a small, early-stage observational study with only 75 participants, so results may not apply to everyone. It does not test a new drug or treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UZ Leuven
Leuven, Vlaams-Brabant, 3000, Belgium
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