New injection shows promise for heel pain relief

NCT ID NCT05592990

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tested a single injection of NGI226 microparticles in 45 people with Achilles tendinopathy (mid-portion tendon pain). The goal was to see if the injection is safe and helps the tendon heal better than a placebo. Researchers measured side effects and changes in tendon stiffness using ultrasound.

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Contacts and locations

Locations

  • Advanced Research LLC

    Deerfield Beach, Florida, 33064, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Novartis Investigative Site

    Caluire-et-Cuire, 69300, France

  • Novartis Investigative Site

    Berlin, 10117, Germany

  • Novartis Investigative Site

    Hamburg, 20149, Germany

  • Novartis Investigative Site

    Hamburg, 22415, Germany

  • Tucson Orthopedic Institute PC

    Tucson, Arizona, 85712, United States

Conditions

Explore the condition pages connected to this study.