Can adding chemo to radiation keep cervical cancer from coming back?

NCT ID NCT05277688

NEW Recruiting now Disease control Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Aug 18, 2026 · Last updated Aug 18, 2026

Summary

This trial is testing whether adding chemotherapy to radiation therapy after surgery helps prevent cervical cancer from returning in patients with certain intermediate-risk factors. Participants are adults aged 18 to 80 with early-stage cervical cancer who have had a hysterectomy. Half will receive radiation alone, and half will receive radiation plus weekly cisplatin. The study will compare recurrence-free survival over five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cisplatin (chemotherapy) given alongside radiation therapy
What this could lead to: If adding chemo to radiation works, it could lower the chance of cervical cancer returning after surgery, potentially improving long-term survival.
What could go wrong: This is a phase III trial, but results are not yet known. Adding chemo may increase side effects without improving outcomes, and the benefit may only apply to certain patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CERVICAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER

Contacts and locations

Locations

Ruijin Hospital, Shanghai jiaotong univestigy school of medicine
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200025, China
Ruijin Hospital, Shanghai jiaotong univestigy school of medicine
RECRUITING

Shanghai, Shanghai Municipality, 200025, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.