New Alzheimer's vaccine shows promise in Early-Stage trial

NCT ID NCT03461276

First seen May 12, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This study tested a vaccine called ABvac40 in 134 people with very mild Alzheimer's or mild cognitive impairment. The vaccine aims to train the immune system to attack a specific protein (Aβ40) linked to Alzheimer's. The main goal was to check safety and immune response over 24 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Barcelona Beta Brain Research Center (BBRC)

    Barcelona, Barcelona, 08005, Spain

  • CHU de Montpellier

    Montpellier, 34295, France

  • CUN - Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Cae Oroitu

    Algorta, Vizcaya, 48993, Spain

  • Centre de Recherche Clinique du Gérontopôle

    Toulouse, 31059, France

  • Complejo Hospitalario Ruber Juan Bravo

    Madrid, Madrid, 28006, Spain

  • Fundació ACE

    Barcelona, Barcelona, 08028, Spain

  • Hospital Clínico San Carlos

    Madrid, Madrid, 28040, Spain

  • Hospital Clínico Universitario Lozano Blesa

    Zaragoza, Zaragoza, 50009, Spain

  • Hospital General Universitario de Alicante

    Alicante, Alicante, 03010, Spain

  • Hospital Mútua de Terrasa

    Terrassa, Barcelona, 08221, Spain

  • Hospital Ramón y Cajal

    Colmenar Viejo, Madrid, 28034, Spain

  • Hospital San Pedro

    Logroño, La Rioja, 26006, Spain

  • Hospital Santa Maria de Lleida

    Lleida, Lleida, 25198, Spain

  • Hospital U. de Burgos

    Burgos, Burgos, 09006, Spain

  • Hospital Universitario 12 Octubre

    Madrid, Madrid, 28010, Spain

  • Hospital Universitario Donosti

    Donostia / San Sebastian, Guipuzcoa, 20014, Spain

  • Hospital Vall d'Hebron

    Barcelona, Barcelona, 08035, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Barcelona, 08025, Spain

  • Hospital del Mar

    Barcelona, Barcelona, Spain

  • Hôpital François Mitterrand

    Dijon, Bourgogne-Franche-Comté, 21000, France

  • Karolinska Universitetssjukhuset

    Stockholm, 141 86, Sweden

  • San Giovanni di Dio - Fatebenefratelli

    Brescia, 25125, Italy

Conditions

Explore the condition pages connected to this study.