New combo aims to boost radiation therapy in tough prostate cancer

NCT ID NCT05113537

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 27 times

Summary

This study tests whether giving a drug called abemaciclib before a targeted radiation therapy (177Lu-PSMA-617) can make the radiation work better for men with advanced prostate cancer that has stopped responding to other treatments. About 30 participants will receive the combination to find the safest dose and see if it improves cancer control. The goal is to increase the cancer cells' uptake of the radiation, potentially killing more tumor cells.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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