Could a plant hormone help tame prediabetes?
NCT ID NCT04722354
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small phase 2 trial tested whether taking abscisic acid (ABA), a natural plant hormone, can improve how the body handles sugar in people with prediabetes. Five adults with elevated fasting glucose or HbA1c took ABA and had their insulin sensitivity measured using a precise clamp technique. The study monitored side effects and changes in glucose disposal to see if ABA might help manage blood sugar.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
abscisic acid (ABA)
What this could lead to
If it works, this could point toward a natural supplement to help control blood sugar in people with prediabetes.
What could go wrong
This is a very small, early-phase trial with only 5 participants, so results may not apply broadly. The intervention is a plant hormone, and its effects on humans are not well established.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AdventHealth Translational Research Institute
Orlando, Florida, 32803, United States