New cancer drug AB598 enters early human safety testing

NCT ID NCT05891171

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 19 times

Summary

This early-phase study tests the safety of a new drug called AB598, given alone or with other treatments, in about 40 people with advanced solid tumors (e.g., lung, bladder, breast, or ovarian cancer). The main goal is to see if the drug is safe and tolerable. Participants must have measurable tumors and be in relatively good health. This is not a cure but aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Adelaide Cancer Research

    Adelaide, Australia

  • Affinity Health Hope and Healing Cancer Services, LLC

    Hinsdale, Illinois, 60521, United States

  • Gabrail Cancer Center (GCC) Canton Facility

    Canton, Ohio, 44718, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Lake City Cancer Care, LLC.

    Lake City, Florida, 32024, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • National Cheng Kung University Hospital

    Tainan, Taiwan

  • Next Oncology Dallas

    Irving, Texas, 75039, United States

  • Next Oncology Virginia

    Fairfax, Virginia, 22031, United States

  • Queen Elizabeth Hospital

    Adelaide, Australia

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08901, United States

  • Taipei Veterans General Hospital

    Taipei, Taiwan

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.