New MRI scan could spare liver patients from painful needle procedure

NCT ID NCT07554183

Not yet recruiting Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special 4D-flow MRI can accurately measure blood flow and pressure in the liver without needing an invasive catheter. Researchers will enroll 60 adults with cirrhosis and compare MRI results to the standard pressure test. If it works, this could make diagnosis safer and more accessible for patients with portal hypertension.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 4D-flow MRI with gadolinium contrast
What this could lead to: If successful, this could provide a non-invasive way to diagnose and monitor portal hypertension, reducing the need for risky catheter procedures.
What could go wrong: This is a small, early-stage diagnostic study with only 60 participants. The MRI technique may not prove accurate enough to replace the current gold standard, and results may not apply to all cirrhosis patients.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis hepatic encephalopathy portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRRHOSIS PORTAL HYPERTENSION

Contacts and locations

Locations

Hôpital Pitié Salpêtrière

Paris, 75013, France

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