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Custom 3D-Printed stents could spare kids with brain cancer from painful mouth sores

NCT ID NCT07715357

Not yet recruiting Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This trial tests whether custom 3D-printed intraoral stents can protect the mouth from radiation damage in children with medulloblastoma, a type of brain cancer. During radiotherapy, the stent is worn inside the mouth to physically move healthy tissue away from the radiation beam. The study aims to see if this reduces painful mouth sores, gum problems, and cavities, and improves the child's quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
custom-designed 3D-printed intraoral stent made of medical-grade resin
What this could lead to
If effective, this could become a standard way to prevent severe mouth sores in children receiving brain radiation, improving their quality of life during treatment.
What could go wrong
This is a relatively small, early-stage trial, and the benefit may vary depending on each child's anatomy and radiation plan. The stents must be comfortable enough for children to wear daily.

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Conditions

The condition(s) this trial relates to.

medulloblastoma mucositis radiation injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MEDULLOBLASTOMA TUMOR MUCOSITIS RADIATION INJURIES

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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