Simple scope procedure may prevent radiation damage in recurrent nose cancer

NCT ID NCT07552883

Not yet recruiting Prevention Sponsor: Jiangxi Provincial Cancer Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether removing a thin layer of tissue (pseudomembrane) from the back of the nose using a scope can prevent radiation-induced tissue death in patients with recurrent nasopharyngeal cancer who have had repeat radiation. About 40 adults in China will undergo the procedure. The goal is to cut the 2-year risk of tissue death from the expected 40% down to 20%.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Endoscopic nasopharyngeal pseudomembrane removal
What this could lead to: If it works, this simple procedure could significantly lower the risk of severe nasal tissue damage after repeat radiation for recurrent nasopharyngeal cancer.
What could go wrong: This is a small, early-stage study with only 40 participants and no comparison group, so results may not be definitive. The procedure itself carries risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma Necrosis radiation injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASOPHARYNGEAL CARCINOMA (NPC) NECROSIS RADIATION INJURIES

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