Yongquan Shi

This study tests if upadacitinib, a newer pill, works as well as standard steroid injections for treating sudden, severe flare-ups of ulcerative colitis. About 46 adults with acute severe colitis will receive either upadacitinib or steroids for 3 months, with frequent checkups. T…

This study tests whether thalidomide combined with glutamine can reduce bleeding in people with chronic radiation injury to the intestines. 150 adults who have rectal bleeding after past radiation therapy will take one or both drugs for 8 weeks. The goal is to see if the combinat…

This study tests whether ursodeoxycholic acid, a bile acid medication, can reverse gastric intestinal metaplasia—a condition where the stomach lining changes and raises cancer risk. Researchers will give 196 adults without H. pylori infection either the drug or a placebo for 6 mo…

This study tests whether adding a probiotic called Saccharomyces boulardii to a standard antibiotic cocktail helps clear Helicobacter pylori infections that didn't respond to earlier treatments. About 1,248 adults who have failed prior H. pylori therapy will be randomly assigned …

This study is investigating whether exposure to microplastics is linked to the development of stomach cancer and its early stages. Researchers will ask 450 people with different stomach conditions to fill out a detailed questionnaire about their possible exposure to microplastics…