Can a common bile acid pill reverse stomach changes that lead to cancer?
NCT ID NCT06610760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether ursodeoxycholic acid, a bile acid medication, can reverse gastric intestinal metaplasia—a condition where the stomach lining changes and raises cancer risk. Researchers will give 196 adults without H. pylori infection either the drug or a placebo for 6 months, checking every 4 weeks. The goal is to see if the drug can make the abnormal tissue regress or prevent it from worsening.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ursodeoxycholic acid
What this could lead to
If it works, this could offer a non-invasive way to reverse a precancerous stomach condition, potentially reducing stomach cancer risk.
What could go wrong
This is a phase 4 trial, but the condition is hard to reverse and previous treatments have had mixed results. The benefit may be small or absent, and side effects are possible.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GASTRIC INTESTINAL METAPLASIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
989 Hospital of PLA Joint Logistics Support Force
RECRUITINGPingdingshan, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Ankang Central Hospital
RECRUITINGAnkang, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Hanzhong 3201 Hospital
RECRUITINGHanzhong, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Shangluo Central Hospital
RECRUITINGShangluo, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Xi'an Central Hospital
RECRUITINGXi'an, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Xijing hospital
RECRUITINGXi'an, Shaanxi, 710032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••