New pill may replace steroids for severe colitis flares
NCT ID NCT07546097
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if upadacitinib, a newer pill, works as well as standard steroid injections for treating sudden, severe flare-ups of ulcerative colitis. About 46 adults with acute severe colitis will receive either upadacitinib or steroids for 3 months, with frequent checkups. The goal is to see if upadacitinib can quickly calm symptoms like diarrhea and bleeding with fewer side effects, though ongoing medication is still needed to manage the disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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3201 Hospital
RECRUITINGHanzhong, Shaanxi, 710005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ankang Central Hospital
RECRUITINGAnkang, Shaanxi, 710005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shaanxi Provincial Nuclear Industry 215 Hospital
RECRUITINGXianyang, Shaanxi, 710005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xijing Hospital
RECRUITINGXi'an, Shaanxi, 710005, China
Contact Phone: •••-•••-•••• Email: •••••@•••••