Versailles Hospital

This phase 2 trial is testing whether combining two drugs, ponatinib and 5-azacitidine, can improve survival in people with advanced chronic myeloid leukemia (CML). The study includes adults whose CML has progressed to an accelerated phase or a more aggressive blast crisis. Parti…

This study tests whether adjusting the daily dose of the leukemia drug dasatinib based on a patient's blood levels can improve safety and effectiveness. Adults newly diagnosed with chronic phase chronic myeloid leukemia (CML) will receive either standard dosing or a dose tailored…

This phase 2 trial tests whether adding pioglitazone (a diabetes drug) to the standard leukemia medication imatinib can eliminate remaining cancer cells in people with chronic-phase chronic myeloid leukemia (CML). Participants must have been on imatinib for at least two years and…

This trial tests whether adding the targeted drug ponatinib to standard chemotherapy (cytarabine) can help prevent relapse in adults with a specific, high-risk genetic form of acute myeloid leukemia (FLT3-ITD AML) who are already in first remission. The study includes two age gro…

This trial investigates whether adjusting the dose of imatinib (Gleevec) based on the drug's level in the blood can improve outcomes for people newly diagnosed with chronic phase chronic myeloid leukemia (CML). Participants whose imatinib blood level is low after 28 days are rand…

This study tests whether adding the targeted drug inotuzumab ozogamicin to a milder chemotherapy regimen improves survival in adults over 55 with a specific type of acute lymphoblastic leukemia (ALL) that is Philadelphia chromosome-negative and CD22-positive. Participants receive…

This trial tests whether a cold spray (cryotherapy) can numb the skin and reduce pain when drawing blood from an artery in intensive care patients. About 200 adults in the ICU who need an arterial blood gas test will receive the spray before the puncture. The study measures pain …

This study translated and tested a French version of a parent questionnaire designed to identify problematic social media use in children aged 10 to 17. Researchers recruited 300 parent-teen pairs from a hospital in France. The goal is to give parents a reliable way to spot unhea…

This completed study from Versailles Hospital looked back at 200 medical reports of adults with skin injuries like cuts, scrapes, burns, and leg ulcers. The goal was to see how well pain was controlled during treatment. Researchers also interviewed some patients and staff to chec…