Cold spray could take the sting out of blood gas tests

NCT ID NCT03973385

Completed Symptom relief Sponsor: Versailles Hospital Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial tests whether a cold spray (cryotherapy) can numb the skin and reduce pain when drawing blood from an artery in intensive care patients. About 200 adults in the ICU who need an arterial blood gas test will receive the spray before the puncture. The study measures pain levels and how easy the procedure is for healthcare workers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryotherapy (vapocoolant spray)
What this could lead to: If effective, this cold spray could offer a simple, drug-free way to reduce pain during a common ICU procedure.
What could go wrong: This is a small, early-stage trial. The cold spray may not significantly reduce pain, and results may not apply to all patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRYOTHERAPY EFFECT

Contacts and locations

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Locations

CHU Saint LOUIS

Paris, 75010, France
Ch Versailles

Le Chesnay, 78150, France
Hopital Européèn Georges Pompidou

Paris, 75015, France
Hopital Nord Franche-Comte

Belfort, 90015, France

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