Vanderbilt University

This study is testing whether adding a specific long-acting insulin (detemir) to a low-calorie diet helps people with type 2 diabetes and obesity lose more weight than dieting alone. Researchers want to see if the insulin works by changing brain activity related to pleasure and r…

This study is testing whether gentle electrical stimulation of a nerve through the skin of the ear can help people with Postural Tachycardia Syndrome (POTS). POTS causes a rapid heart rate and disabling symptoms like dizziness and fatigue when standing. Researchers want to see if…

This study is testing whether a specific classroom teaching program improves 4th graders' understanding of fractions. It involves about 2,210 students, including those with and without math learning difficulties. Teachers are randomly assigned to either use the new fraction lesso…

This study aims to understand if people with Postural Tachycardia Syndrome (POTS) have different levels of certain antibodies and markers of inflammation in their blood compared to people without POTS. Researchers at Vanderbilt University are enrolling 212 participants, including…

This study is testing whether measuring specific substances in blood samples taken during a standard heart catheterization procedure can help doctors make more informed treatment choices for pulmonary hypertension. Researchers will analyze blood from 100 adults already scheduled …

This research project aims to understand the genetic and biological roots of serious mental health conditions like major depression, bipolar disorder, and psychotic disorders. It involves collecting DNA, brain scans, and detailed health information from 2,000 participants, includ…

This study aims to understand how people with chronic dizziness and rapid heartbeat when standing (called orthostatic intolerance or POTS) process salt differently than healthy people. Researchers will compare 30 participants—some with the condition and some healthy controls—by m…

This study aims to understand why people with sickle cell disease sometimes struggle to take their daily medication. Researchers will interview patients to identify common barriers like cost, forgetfulness, or side effects. They will then work with patients to design and test per…

This study aims to understand why many intensive care unit (ICU) patients develop severe, long-lasting muscle weakness. Researchers will examine 50 critically ill patients using muscle ultrasounds, blood tests, and small muscle samples to learn how this weakness develops. The goa…

This study aims to learn more about nonalcoholic fatty liver disease (NAFLD), a common liver condition linked to obesity and diabetes. Researchers will analyze small pieces of liver tissue from 45 adults who are already having abdominal surgery. By measuring the specific fats and…

This study aims to understand how blood flow in abdominal veins contributes to blood pressure problems in people with Multiple System Atrophy, a rare nervous system disorder. Researchers will study about 16 participants with both low blood pressure when standing and high blood pr…

This study is screening women with suspected Postural Tachycardia Syndrome (POTS) to understand their condition better. It involves detailed tests to measure blood volume, hormone levels, and nervous system function. The goal is to gather information for future research on whethe…