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This study tests a new treatment called ADP-A2M4CD8 for people with certain cancers (like lung, ovarian, or melanoma) that have a specific protein (MAGE-A4) and a matching immune type (HLA-A2). The treatment uses the patient's own immune cells, modified to attack the cancer. The …

This study tests a new treatment called ADP-A2M4 for people with advanced synovial sarcoma or myxoid liposarcoma that has spread or cannot be removed. The treatment uses a patient's own immune cells that are genetically modified to recognize and attack cancer cells. The study aim…

This phase 2 trial tests a treatment called Lete-Cel, which uses a patient's own immune cells that have been specially trained to attack cancer cells. It is for people with advanced synovial sarcoma or myxoid/round cell liposarcoma whose tumors have a specific marker (NY-ESO-1) a…

This early-phase study tests a personalized cell therapy for people with certain cancers (bladder, melanoma, head/neck, ovarian, lung, esophageal, stomach, or sarcoma) whose tumors have a specific marker called MAGE-A4. The treatment involves taking a patient's own immune cells, …

This study tests a new treatment called ADP-A2M4CD8, made from a patient's own immune cells, for ovarian cancer that has returned. It is given alone or with another drug (nivolumab) to see if it can shrink tumors. About 66 people with a specific genetic marker (HLA-A*02 and MAGE-…

This study tests a new treatment using a patient's own immune cells that are genetically modified to better recognize and attack certain solid tumors. It is for people with advanced cancers like synovial sarcoma that have not responded to other treatments. The goal is to see if t…