University Of Oxford

This study tested the Oxford COVID-19 vaccine (ChAdOx1 nCoV-19) in over 10,000 healthy adults aged 18 and older. The goal was to see if the vaccine could prevent symptomatic COVID-19 and to check for any serious side effects. Participants received the vaccine and were monitored f…

This study tested a new, easy-to-take ivermectin tablet in 13 children with scabies who weighed between 11 and 33 pounds. The goal was to see if the medicine is safe, how the body processes it, and if it works. The results will help expand scabies treatment to younger children wh…

This study tested whether using three drugs together (triple therapy) works as well as the standard two-drug treatment for uncomplicated malaria in children across Africa. Over 2,500 children aged 6 months to 12 years took part. The goal was to see if the triple combination could…

This early-phase trial tested the safety of adding atovaquone, a drug used for malaria, to standard chemoradiotherapy for people with locally advanced non-small cell lung cancer. The goal was to find the safest dose and see if it helps control the disease. Twenty-one participants…

This study tested three different treatment plans for people newly diagnosed with moderate to severe psoriatic arthritis. One group received standard care, another got a combination of early disease-modifying drugs, and the third started with a stronger biologic therapy. The goal…

This study tested whether an online program called Sleepio, which teaches cognitive behavioral therapy for insomnia, can improve sleep in people who have had a stroke. 86 chronic stroke survivors who wanted better sleep were split into two groups: one got access to Sleepio, the o…

This study tested whether 'Hope Groups'—small, peer-led support groups—can help Ukrainian caregivers affected by war. Over 500 adults took part, with some joining groups and others on a waitlist. The goal was to see if these groups improve mental health, reduce violence against c…

This study looked at 48 ICU patients on breathing machines to understand how doctors can better reopen collapsed parts of the lung. Researchers measured lung volume before and after a procedure that briefly increases airway pressure. The goal was to find which features of a press…

This study tested a wireless monitoring system that tracks vital signs like heart rate and breathing continuously, without wires or bed rest. The goal was to see if it helps hospital staff detect when surgical patients are getting worse more quickly than standard checks every few…