Massive oxford vaccine trial shows promise against COVID-19

NCT ID NCT04400838

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This study tested the Oxford COVID-19 vaccine (ChAdOx1 nCoV-19) in over 10,000 healthy adults aged 18 and older. The goal was to see if the vaccine could prevent symptomatic COVID-19 and to check for any serious side effects. Participants received the vaccine and were monitored for several months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CCVTM, University of Oxford, Churchill Hospital

    Oxford, OX3 7LE, United Kingdom

  • Castle Hill Hospital

    Cottingham, Hull, HU16 5JQ, United Kingdom

  • Glasgow University and NHS Greater Glasgow & Clyde, New Lister Building, Glasgow Royal Infirmary & Queen Elizabeth University Hospital

    Glasgow, G31 2ER, United Kingdom

  • Guy's and St Thomas' NHS Foundation Trust, Department of Infection, St Thomas Hospital

    London, SE1 7EH, United Kingdom

  • Imperial College Healthcare NHS Trust

    London, W12 0HS, United Kingdom

  • John Radcliffe Hospital

    Oxford, OX3 9DU, United Kingdom

  • Liverpool School of Tropical Medicine (LSTM), Accelerator Research Clinic. Clinical Sciences Accelerator

    Liverpool, L7 8XZ, United Kingdom

  • London North West University Healthcare Trust (LNWUH), Northwick Park Hospital

    London, HA1 3UJ, United Kingdom

  • NHS Lothian, Western General Hospital

    Edinburgh, EH4 2XU, United Kingdom

  • NIHR Cambridge Clinical Research Facility

    Cambridge, CB2 0QQ, United Kingdom

  • North Bristol NHS Trust

    Bristol, United Kingdom

  • Public Health Wales

    Newport, NP18 3XQ, United Kingdom

  • Sheffield Teaching Hospitals, Royal Hallamshire Hospital

    Sheffield, S10 2RX, United Kingdom

  • St Georges University Hospital NHS Foundation Trust

    London, Tooting, SW17 0QT, United Kingdom

  • The Newcastle upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary

    Newcastle upon Tyne, NE1 4LP, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    London, NW1 2PG, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, Hampshire, SO16 6YD, United Kingdom

  • University Hospitals Birmingham NHS Foundation Trust

    Birmingham, United Kingdom

  • University Hospitals Bristol and Weston NHS Foundation Trust

    Bristol, BS1 3NU, United Kingdom

  • University of Nottingham Health Service, Cripps Health Centre, University Park

    Nottingham, NG7 2QW, United Kingdom

Conditions

Explore the condition pages connected to this study.