University Of Chile

This phase 3 study tests whether three doses of an oral rotavirus vaccine (ROTAVAC 5D) can prevent severe diarrhea in healthy infants. Around 4,270 Chilean babies receive either the vaccine or a placebo. Researchers track cases of severe rotavirus gastroenteritis to measure the v…

This study tested whether sending WhatsApp messages that offer a discount or suggest scheduling a dental check-up on the same day as a medical appointment increases preventive dental care. Over 300,000 adults in Chile who had a medical visit coming up and hadn't seen a dentist in…

This completed trial tested a personalized sound therapy for adults with chronic tinnitus, a condition where people hear ringing or buzzing without an external source. 25 participants received either music embedded with tones matched to their tinnitus frequency or low-frequency s…

This study tested whether teaching people about pain during light cycling helps chronic low back pain more than cycling alone. 24 adults with long-term back pain were split into two groups: one cycled while learning about pain, the other just cycled. Researchers measured pain, pr…

This study tested two ways to numb the shoulder after surgery: the standard interscalene block and a combination of two other blocks (infraclavicular and anterior suprascapular). The goal was to see if the combination could provide equal pain relief without causing temporary diap…

This study tested a short psychological program called Problem Management Plus (PM+) for adults with depression or anxiety in a primary care clinic in Chile. The program involves five 90-minute sessions teaching problem-solving and stress management skills, delivered by healthcar…

This pilot study tested a prototype device that automatically gives the sedative propofol to deeply sedated patients in the ICU who are on breathing machines. The goal was to see if the device could keep patients at the right sedation level while using less medication compared to…

This study tested whether restricting eating to a 10-hour daily window improves blood sugar, appetite, and body clock function in night shift workers. Twenty-two healthcare workers followed the eating schedule for 8 weeks, then their usual diet for another 8 weeks. The goal was t…

This study observed 49 adults hospitalized with acute heart failure to learn how fluid congestion behaves during treatment. Researchers tracked clinical signs, lab tests, and ultrasound measures, then followed patients for a year to see who was readmitted or died. The goal is to …

This study looked at 57 adults having laparoscopic abdominal surgery to see if specific brain wave patterns during surgery are linked to how much pain they feel afterward. Researchers measured pain levels and painkiller use after surgery. The goal was to better understand pain, n…

This study looked at whether a special stitching technique (periosteal sutures) helps bone grafts heal better when placing dental implants in the upper front jaw. Forty adults who needed implants and bone grafting took part. The main goal was to measure bone thickness around the …

This study tested whether a mobile app with educational videos and games could improve older adults' knowledge about oral cancer and oral hygiene. Sixty-two adults aged 60 and older used either a version with videos and games or just videos for 4 weeks. The goal was to see if the…

This study measured inflammation markers and brain activity in 20 older adults during elective surgery. Researchers wanted to see if these factors could be early signs of Alzheimer's disease. The study is complete and aimed at understanding, not treating, the disease.