New automated sedation system aims to use less medicine in ICU

NCT ID NCT06187545

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested a prototype device that automatically gives the sedative propofol to deeply sedated patients in the ICU who are on breathing machines. The goal was to see if the device could keep patients at the right sedation level while using less medication compared to usual care. Twenty patients took part, and the study compared the amount of propofol used and sedation levels between the two approaches.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
propofol
What this could lead to
If it works, this could lead to a smarter way to sedate ICU patients, using less medication and possibly reducing side effects.
What could go wrong
This is a very small pilot study with only 20 patients, so results may not apply to everyone. The device is still a prototype and may not work better than usual care.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile

    Santiago, RM, 7690306, Chile

  • Hospital Base San José Osorno

    Osorno, Los Lagos Region, Chile

  • Hospital Clinico de la Universidad de Chile

    Santiago, RM, 7690306, Chile

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