University Of Catania

This trial investigates whether a topical clobetasol gel can change the levels of microRNAs in the gum fluid of people with oral lichen planus, a chronic inflammatory condition. Participants will apply either the active gel or a placebo to their lesions, and researchers will comp…

This trial tests whether a mouthwash containing chlorhexidine and sodium DNA can better control bacterial biofilm in people with advanced periodontitis (stage III or IV). Participants will receive standard non-surgical gum treatment plus one of two mouthwashes or a placebo, and r…

This trial investigates whether non-surgical gum treatment can improve early signs of blood vessel dysfunction in people with periodontitis who have no known heart disease. Sixty participants will receive one of two types of deep cleaning procedures. Researchers will measure chan…

This study tested whether an AI-powered chatbot could help people with dental implants take better care of their teeth and gums. 110 adults with implants were split into two groups: one used the chatbot for personalized oral hygiene tips, while the other received standard printed…

This pilot study tested two automated insulin delivery systems (Medtronic 780G and Tandem t:slim X2) in 20 adolescents with type 1 diabetes. Participants ate breakfasts without telling the device how many carbs they were eating. The goal was to see how well each system controlled…