University Of Birmingham

This study tested whether adding bevacizumab (a drug that cuts off a tumor's blood supply) to standard chemotherapy helps children aged 1 to 21 with neuroblastoma that has come back or not responded to treatment. About 225 children took part. The goal was to see if the combinatio…

This trial tested several targeted drugs in people with non-small cell lung cancer whose tumors had specific genetic markers. The goal was to see if these drugs could shrink tumors or delay cancer growth. Over 400 participants received treatment matched to their cancer's genetic …

This study tested the drug sodium valproate in 63 children and adults with Wolfram syndrome, a rare genetic disorder that causes vision loss, diabetes, and other problems. Participants were randomly assigned to receive either the drug or a placebo to see if it could slow the dise…

This study tested the drug nivolumab in 35 people with a certain type of advanced colorectal cancer that had not responded to standard treatments. The goal was to see if the drug could stop the cancer from growing for at least 27 weeks. The trial focused on patients whose cancer …

This study looked at whether a cocoa drink rich in flavanols can protect blood vessel function and blood pressure in healthy older adults who sit for long periods. Twenty participants aged 65 and older drank either a high-flavanol or low-flavanol cocoa before sitting for 2 hours.…