Ucb Biopharma Srl

This study tested whether bimekizumab, an injectable medication, is effective and safe for adults with active nonradiographic axial spondyloarthritis, a type of inflammatory arthritis that primarily affects the spine and causes significant back pain and stiffness. The trial invol…

This large, completed Phase 3 trial tested whether an injectable medication called bimekizumab could help people with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition that causes painful lumps under the skin. Over 500 participants received either the dru…

This study tested whether an injectable medication called bimekizumab could help people with active ankylosing spondylitis, a painful inflammatory arthritis of the spine. Over 300 participants received either the drug or a placebo for 16 weeks to see if it could reduce symptoms l…

This study tested whether a drug called rozanolixizumab could help adults with generalized myasthenia gravis, a disease that causes severe muscle weakness. Researchers compared the drug to a placebo in 200 participants over 43 days to see if it improved their ability to perform d…

This study tested an investigational drug called bimekizumab in adults with moderate to severe plaque psoriasis. It was a large, late-stage trial comparing the drug to a placebo to see how well it cleared skin and reduced symptoms like itch and pain. The main goal was to see if p…

This study tested a new drug called UCB1381 to see if it is safe and if it can help control moderate to severe eczema (atopic dermatitis). First, healthy volunteers received single doses to check for safety. Then, people with eczema received multiple doses over time to see if the…

This study tested whether people with generalized myasthenia gravis (gMG) could safely give themselves their medication at home after training. Researchers taught 62 participants how to use two different injection methods and monitored their success and safety. The goal was to ma…

This study tested whether a new oral medication, UCB0599, could slow the worsening of Parkinson's disease symptoms. It involved 496 people with early-stage Parkinson's who were not yet on standard symptom-relief medications. Participants took either the drug or a placebo for 18 m…

This study tested whether adding a new medication called brivaracetam helps reduce the number of partial seizures in people with epilepsy. It involved 449 participants aged 16 to 80 who were still having seizures despite taking one or two other anti-seizure drugs. The goal was to…

This study tested whether adding an experimental drug called UCB0022 to standard Parkinson's medication could help people with advanced disease. It involved 207 participants who still experienced daily periods where their medication wore off and symptoms returned. The main goal w…

This study tested if people with generalized myasthenia gravis (gMG), a chronic autoimmune disease that causes muscle weakness, could safely switch from receiving their medication through regular intravenous (IV) infusions at a clinic to giving themselves a daily injection (ziluc…

This study tested a new medication called bimekizumab against an existing treatment, adalimumab, for adults with moderate to severe plaque psoriasis. It involved 478 participants and aimed to see which drug was better at clearing skin and improving symptoms. The study also monito…

This study tested whether people with generalized myasthenia gravis (a condition causing muscle weakness) could safely and effectively give themselves their medication using a new auto-injector device at home. Thirty-one adults who were already taking the medication zilucoplan pa…

This study tested if a new drug called bimekizumab works better than an existing drug, secukinumab, for adults with moderate to severe plaque psoriasis. It involved 743 participants and measured how clear their skin became over 48 weeks. The main goal was to see if bimekizumab co…

This study tested an investigational drug called bimekizumab in adults with moderate to severe plaque psoriasis. The main goals were to see how well it cleared skin symptoms, how the drug behaved in the body, and if it was safe. Forty-nine participants received the drug and were …

This study tested a new drug called UCB9741 to see if it is safe and if it can help control moderate-to-severe atopic dermatitis (eczema). First, healthy volunteers received single doses to check safety. Then, people with eczema received repeated doses to see if their skin condit…

This study tested whether a new injectable drug called bimekizumab could safely reduce the joint pain, swelling, and skin symptoms of psoriatic arthritis. It involved 852 adults and compared bimekizumab against a placebo (dummy treatment) and an existing drug, adalimumab. The mai…

This study followed 1,353 adults with moderate to severe plaque psoriasis for up to 3 years to check the long-term safety and effectiveness of the drug bimekizumab. Participants who had completed earlier bimekizumab studies continued receiving the medication in this open-label ex…

This completed Phase 3 trial tested whether the drug bimekizumab could reduce painful skin lesions and improve quality of life for people with moderate to severe hidradenitis suppurativa (HS), a chronic inflammatory skin disease. The study involved 505 adults whose HS did not res…

This study tested whether an injectable drug called bimekizumab could help people with active psoriatic arthritis who hadn't gotten enough relief from their previous standard treatments. It involved 400 participants and compared the drug against a placebo (inactive shot) to see i…

This study aimed to understand the long-term safety and effectiveness of the seizure medication brivaracetam in children and young adults (ages 2-26) with childhood or juvenile absence epilepsy. It followed 84 participants who had previously taken the drug in a related study to s…

This study tested an investigational drug called bimekizumab for adults with moderate to severe plaque psoriasis. It compared bimekizumab against a placebo and an existing treatment to see how well it cleared skin plaques and reduced symptoms like itch and pain. The main goal was…

This study tested whether an injectable drug called bimekizumab is better than a placebo at clearing skin in adults with moderate to severe plaque psoriasis. It involved 133 Chinese participants who received injections for 16 weeks. Researchers measured how much the psoriasis imp…

This was an early-stage study to check the safety and see how the body processes a new drug called UCB9741. It involved 40 healthy adult volunteers from Caucasian and Japanese backgrounds who received a single injection. The main goal was to monitor for any side effects and measu…

This was a first-in-human study to check the safety and see how the body processes a new drug called donzakimig. It involved 32 healthy Chinese and Japanese volunteers who received a single injection. The main goal was to see if the drug was safe and well-tolerated at two differe…

This study aimed to understand how the body absorbs two new versions of an experimental drug called UCB0599, and to see if a common heartburn medicine affects this process. It also tested the drug's safety and how it moves through the body in healthy volunteers of Japanese and Ch…

This study tested whether a drug called zilucoplan works the same way in the body when injected using a standard syringe versus a new auto-injector device. It involved 14 healthy adults who received the drug both ways. The main goal was to see if the auto-injector delivers the dr…

This was the first study in humans to test the safety of a new experimental drug called UCB0022 for Parkinson's disease. Researchers gave different doses to 100 healthy volunteers and people with Parkinson's to check for side effects and see how the body processes the drug. The s…

This study tested a new tablet version of the drug minzasolmin to see how well it gets into the bloodstream compared to an older capsule form. It also checked if taking the new tablet with food changes how the body processes the drug. The study involved 18 healthy adult volunteer…

This study aimed to see if a new version of an experimental pill (UCB0022) gets into the bloodstream as well as the original version. Fourteen healthy adults took both pill versions at different times so researchers could compare them. The main goal was to measure how much of the…

This study tested how quickly three different anxiety/seizure medications start working in the brain. Researchers gave healthy volunteers either an inhaled alprazolam, an injected midazolam, or a nasal spray diazepam and measured brain wave changes. The goal was to see which medi…