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Trevi Therapeutics

Clinical trials sponsored by Trevi Therapeutics, explained in plain language.

Trials to join now! 2 Not yet recruiting 2 Completed 4
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  • New pill aims to silence stubborn chronic cough

    Symptom relief Not yet recruiting

    This study tests a new extended-release tablet called nalbuphine for people with refractory chronic cough—a cough that persists despite treatment. About 100 adults will receive either the drug or a placebo for 6 weeks. The main goal is to see if the drug reduces how often people …

    Phase: PHASE2 • Sponsor: Trevi Therapeutics • Aim: Symptom relief

    Last updated Jun 28, 2026 00:00 UTC

  • Could a painkiller stop the cough that Won't quit in lung fibrosis?

    Symptom relief Not yet recruiting

    This study tests whether an extended-release form of nalbuphine, a pain medication, can safely reduce chronic coughing in people with idiopathic pulmonary fibrosis (IPF), a lung scarring disease. About 306 adults with IPF and a cough lasting at least 8 weeks will receive either t…

    Phase: PHASE3 • Sponsor: Trevi Therapeutics • Aim: Symptom relief

    Last updated Jun 28, 2026 00:00 UTC

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