The Netherlands Cancer Institute

This study is comparing two different schedules of radiation therapy given before surgery for soft tissue sarcoma. Researchers want to see if a shorter, 3-week course of radiation works as well as the standard 5-week course at preventing the cancer from coming back and causes sim…

This study is for people with advanced triple-negative breast cancer, a hard-to-treat type. It tests if adding an immunotherapy drug (atezolizumab) to standard first-line chemotherapy helps control the cancer better and for longer. Researchers also want to learn which patients ar…

This study was designed to test a new two-drug combination for people with advanced colorectal cancer that had stopped responding to standard chemotherapy. The goal was to see if adding an experimental drug (LY3200882) to an existing chemotherapy pill (capecitabine) could help co…

This study is for people with advanced non-small cell lung cancer whose disease progressed after standard immunotherapy. Researchers want to see if adding a different immunotherapy drug (ipilimumab) and targeted radiation to a few tumors can help patients respond again to the ori…

This international trial is testing if a more intense, personalized chemotherapy regimen can improve survival and prevent cancer from returning in people with a specific, high-risk type of breast cancer. It compares the standard treatment to a stronger one, which includes a stem …

This study is testing three different combinations of immunotherapy drugs given to patients before surgery for intermediate-to-high-risk kidney cancer. The goal is to see which drug combination best shrinks the tumor and reduces the chance of the cancer coming back after surgery.…

This study is testing a more precise way to deliver radiation to patients with head and neck cancer. Doctors use a special scan to map which lymph nodes are at risk, aiming to avoid radiating healthy areas on the opposite side of the neck. The goal is to control the cancer while …

This study is testing a new, shorter radiation treatment schedule for men with intermediate-risk prostate cancer. The goal is to see if delivering fewer, more precise radiation doses using advanced MRI-guided machines can reduce common side effects like urinary and bowel problems…

This study is testing whether the immunotherapy drug pembrolizumab can shrink tumors in people with a specific type of locally advanced colon cancer that cannot be surgically removed. It will involve 25 participants who will receive the drug intravenously every three weeks. The m…

This study aims to find out if a 'watchful waiting' approach is as safe as immediate surgery or radiation for women with certain early, non-invasive breast cell changes (low-risk DCIS). It will follow 2,500 women for 10 years, comparing those who choose active monitoring with ann…