Heated chemo during surgery may boost ovarian cancer survival

NCT ID NCT03772028

First seen Apr 10, 2026 · Last updated Apr 28, 2026 · Updated 2 times

Summary

This study tests whether adding heated chemotherapy directly into the abdomen during surgery helps people with stage III ovarian cancer live longer. About 538 participants are randomly assigned to standard surgery alone or surgery plus the heated chemo. The main goal is to see if the extra treatment improves overall survival and delays cancer return.

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Contacts and locations

Locations

  • Alice Bjoernlund-Larsen

    Uppsala, Sweden

  • Amsterdam UMC

    Amsterdam, Netherlands

  • Antoni van leeuwenhoek

    Amsterdam, North Holland, 1066CX, Netherlands

  • CHRU Strasbourg

    Strasbourg, France

  • CHU Lille

    Lille, France

  • CHU Lyon

    Lyon, France

  • CHU de Besancon

    Besançon, France

  • Catharina Hospital

    Eindhoven, Netherlands

  • Centre Leon Berard, Lyon

    Lyon, France

  • City of Hope

    Duarte, California, 91010, United States

  • Erasmus MC

    Rotterdam, Netherlands

  • Fondazione Policlinico A Gemelli IRCCS

    Roma, Italy

  • Institut Bergonié

    Bordeaux, France

  • Institut Curie Paris

    Paris, France

  • Institut de Cancerologie de l'Ouest, ICO Nantes)

    Nantes, France

  • Institut du Cancer Montpellier

    Montpellier, France

  • Leiden University Medical Center (LUMC)

    Leiden, Netherlands

  • MSKCC New York

    New York, New York, 10065, United States

  • Maastricht UMC+

    Maastricht, Netherlands

  • Mater Misericordiae University Hospital, Dublin

    Dublin, Ireland

  • Medisch Spectrum Twente

    Enschede, Netherlands

  • Oncopole, Institute Universitaire du Cancer de Toulouse (IUCT Toulouse)

    Toulouse, France

  • Policlinico Sant'Orsola, Bologna

    Bologna, Italy

  • Radboud MC

    Nijmegen, Netherlands

  • Rigshospitalet Copenhagen

    Copenhagen, Denmark

  • UMCG

    Groningen, Netherlands

  • UMCU

    Utrecht, Netherlands

  • o Institut Bergonié, Bordeaux

    Bordeaux, France

Conditions

Explore the condition pages connected to this study.