Tel-aviv Sourasky Medical Center

This phase 2 trial tests a drug called mosunetuzumab, given as a shot under the skin, for people with a slow-growing type of lymphoma that hasn't been treated yet. The drug works by helping the body's immune cells find and kill cancer cells. About 30 adults will receive up to 8 c…

This study tests whether the drug everolimus can help women with a common type of advanced breast cancer (HR-positive, metastatic) whose cancer has stopped responding to a similar drug called alpelisib. The trial will enroll 19 women and measure how many see their tumors shrink. …

This early-stage trial tests whether adding a drug called CLS-015 to standard CAR-T cell therapy can help people with large B-cell lymphoma whose disease is stable or getting worse. CLS-015 works by breaking down NETs, which are immune-trapping webs that may block CAR-T cells. Th…

This study tests whether MRI scans can identify triple-negative breast cancer patients who respond well to initial chemotherapy and immunotherapy, allowing them to skip the second, more toxic phase of treatment. About 54 participants will receive four cycles of a chemo-immunother…

This early-stage pilot study is testing whether psilocybin, a psychedelic compound, can be safely combined with trauma-focused psychotherapy for people with post-traumatic stress disorder (PTSD). Thirteen participants will receive two doses of psilocybin in a controlled setting, …

This pilot study tests whether a smartphone app called Walking Tall can help people with Parkinson's disease improve their walking. Thirty participants will use the app at home for 6 weeks, doing walking exercises with audio cues and prompts. Researchers will measure step counts,…

This study looks at how many calories patients with head and neck cancer need before and after free flap reconstructive surgery. Researchers will use indirect calorimetry to measure energy use at several time points, along with body composition and diet questionnaires. The goal i…

This study is looking for 2,000 people who have a close family member with a blood cancer like multiple myeloma. The goal is to find early warning signs of the disease by collecting blood samples and health information over time. Participants will not receive any treatment, but t…