New shot targets lymphoma without chemo

NCT ID NCT07191249

Recruiting now Disease control Sponsor: Tel-Aviv Sourasky Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This phase 2 trial tests a drug called mosunetuzumab, given as a shot under the skin, for people with a slow-growing type of lymphoma that hasn't been treated yet. The drug works by helping the body's immune cells find and kill cancer cells. About 30 adults will receive up to 8 cycles of treatment over roughly 6 months, and researchers will track how well the cancer responds and what side effects occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mosunetuzumab (a drug that helps immune cells attack cancer cells)
What this could lead to: If successful, this could offer a less intensive first-line treatment option for people with a slow-growing form of lymphoma, potentially delaying the need for stronger therapies.
What could go wrong: This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The drug may cause side effects like infusion reactions or infections, and it's not yet known if it works better than current approaches.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FOLLICULAR LYMPHOMA

Contacts and locations

Locations

Rambam Health Care Campus
RECRUITING

Haifa, Israel
Shaare Zedek Medical Center
RECRUITING

Jerusalem, Israel
Tel Aviv Sourasky Medical Center (TASMC) - Ichilov
RECRUITING

Tel Aviv, Israel
The Hadassah University Hospital-Ein Kerem
RECRUITING

Jerusalem, Israel

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