Tan Tock Seng Hospital

This study tests whether stable hospital patients with a Gram-negative bloodstream infection can safely switch from intravenous (IV) antibiotics to oral pills within 72 hours, instead of continuing IV therapy. Researchers will compare death rates and other outcomes at 30 and 90 d…

This study tests a device called CRYSTALSIGHT that tracks eye movements to detect if wet age-related macular degeneration (AMD) has come back. About 60 adults aged 55 to 99 who are being treated for wet AMD will use the device at home. The goal is to see if it works as well as th…

This study tests whether a mild electrical current applied to the scalp (tDCS) can improve arm and hand function in people who recently had a stroke. Fifty adults with severe arm weakness within 8 weeks of their first stroke will receive either real or sham stimulation during reh…

This study tests a robotic glove that reads brain signals to help people who have had a stroke move their affected hand and arm. The goal is to improve function and dexterity. The trial will include 60 adults who had a stroke at least 16 weeks ago and have limited hand movement.

This study tests whether watching a short educational video before a planned heart procedure (called PCI) can help lower anxiety. About 144 adults will take part, with some watching the video and others receiving usual care. Anxiety levels are measured before and after using a st…

This study aims to establish what normal binocular single vision (using both eyes together) looks like for healthy adults in Singapore, aged 21 to 59. Current standards are based on a small 1974 study of Caucasians, which may not apply to Asian populations. Researchers will measu…

This study involves giving healthy adult volunteers a weakened form of the dengue virus to safely study how the infection develops and how the immune system responds. The goal is to create a reliable model for testing future dengue vaccines and treatments. Only 5 people will take…