Southeast University, China

This study tests whether switching critically ill patients from full breathing machine support to a partial support mode within 6 hours helps them breathe on their own sooner. About 1,600 adults in ICUs who need a breathing tube for at least 2 days will take part. The goal is to …

This study looks at two ways of feeding patients with severe lung injury (ARDS) who are on a ventilator and lying on their stomach. About 40 adults will be randomly assigned to get nutrition through a tube in the stomach or one in the small intestine. The goal is to see which met…

This study looks at whether using a special imaging tool (EIT) to set the breathing machine's pressure (PEEP) can help people with severe lung injury (ARDS) who are likely to benefit from it. The trial will compare this method to the standard approach in 264 adults. The main goal…

This study looks at patients with acute brain injury who need a breathing machine. Doctors want to find better ways to predict when these patients can safely breathe on their own. The goal is to create a tool that helps decide the right time to remove the breathing tube, reducing…

This study looks at 500 adults with a severe lung condition called ARDS to see if they can be grouped into two types based on their body's inflammation levels. The goal is to find out if knowing a patient's subtype can help doctors choose the best treatments, like fluids, breathi…

This study observes 1,500 adults with acute brain injury who need a breathing machine (ventilator) for at least 24 hours. Researchers want to understand how and when patients are safely taken off the ventilator, and what affects their recovery. The goal is to find better ways to …

This study observes 1,000 adults in intensive care with moderate-to-severe acute respiratory distress syndrome (ARDS) to learn how prone positioning (lying face down) affects survival and recovery. Researchers will explore whether lung shape on CT scans can guide treatment, and w…