Sheffield Children's Nhs Foundation Trust
Clinical trials sponsored by Sheffield Children's Nhs Foundation Trust, explained in plain language.
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New MRI gas test could spare kids from risky lung procedures
Diagnosis Recruiting nowThis study tests a special MRI scan that uses xenon gas to find blockages in the lungs of children with protracted bacterial bronchitis (PBB), a condition causing a long-lasting wet cough. Current diagnosis often requires a bronchoscopy (camera in lungs under anesthesia) or a CT …
Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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New dye test could save testicles and spare thousands of boys from needless surgery
Diagnosis Recruiting nowThis study tests a new imaging method using a safe dye called indocyanine green (ICG) to quickly tell if a child's testicular pain is due to torsion (twisted testicle) or something else. About 85% of children who have surgery for testicular pain don't actually have torsion. The g…
Phase: PHASE4 • Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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Heat-Sensing camera could speed up infection diagnosis in kids
Diagnosis Recruiting nowThis study explores whether a special thermal camera can help doctors quickly detect infections in children's bones, joints, or soft tissues. About 30 children with suspected infections will have a 10-second video taken of the affected area to see if the heat pattern matches the …
Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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Asthma attack study seeks best steroid dose for kids
Symptom relief Recruiting nowThis study compares two different doses of the steroid dexamethasone (0.3 mg/kg vs. 0.6 mg/kg) given by mouth to children aged 4-15 who come to the emergency department with an asthma attack. The goal is to see which dose works better at reducing the need for another steroid pres…
Phase: PHASE4 • Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can PET-MRI spot hidden brain tumors in kids?
Knowledge-focused Recruiting nowThis pilot study is testing whether a combined PET-MRI scan can better detect if a child's brain tumor has returned after treatment. The study will include 5 children with high-grade gliomas or medulloblastomas who have unclear results from standard MRI. The main goal is to see i…
Phase: NA • Sponsor: Sheffield Children's NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC