Seattle Children's Hospital

This early-stage trial tests a new treatment for adults with solid tumors that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to better recognize and attack cancer cells that carry a protein called GPC3. The…

This study looks at 60 infants (1-18 months old) having open-heart surgery to fix a hole between the lower heart chambers (VSD). Normally, the heart-lung machine is filled with donated blood, which may cause inflammation and slow recovery. The trial will compare using a non-blood…

This study tests whether a short pre-game safety huddle can encourage youth soccer players (ages 9-13) to report concussion symptoms. About 2,000 athletes and their coaches will take part. The goal is to see if these huddles increase reporting and help coaches spot possible concu…

This study looks at whether training hospital doctors and nurses in better communication can help more children get their routine vaccines while staying in the hospital. About 2,000 kids and their clinicians will take part. The goal is to see if this training increases the number…

This study tracks 500 people who have received or will receive gene therapy products from Seattle Children's Therapeutics. The goal is to watch for any long-term side effects over up to 15 years. Participants will have regular check-ups and lab tests, but no new treatment is give…

This study tests whether a website called the Family Safety Check-In can help families with children store their firearms more safely. About 548 parents or guardians who have guns at home and currently store them unsafely will be randomly assigned to use the website or not. The g…

This study looks at how two types of birth control devices—copper IUDs and hormonal IUDs—affect the bacteria in the vagina and the risk of infections. About 120 HIV-negative women aged 18-40 will be randomly assigned to one device and followed for a year. Researchers will collect…