Royal Marsden Nhs Foundation Trust

This early-phase trial tested whether adding the drug avelumab (compound 451238) to radiation therapy is safe for people with advanced soft-tissue sarcoma that has spread. Twelve adults with at least two tumors not curable by standard treatments took part. The main goal was to ch…

This early-phase study tested whether combining the immunotherapy drug pembrolizumab with standard palliative radiotherapy is safe for people with advanced lung cancer. Twenty-four participants received different doses of pembrolizumab alongside radiation, then continued pembroli…

This study tested a combination of two drugs, crizotinib and fulvestrant, in 33 people with advanced lobular breast cancer or other cancers linked to a CDH1 gene mutation. The goal was to see if the treatment could shrink tumors and to check for side effects. While both drugs had…

This early-phase study tested an experimental drug called VS-6766, given by mouth on different schedules, in 104 adults with advanced solid tumors or multiple myeloma. The goal was to find a safe and tolerable dose, both when used alone and when combined with another drug (everol…

This study looked at 388 women with advanced ovarian, fallopian tube, or peritoneal cancer who were taking the drug niraparib as ongoing maintenance treatment. Researchers tracked side effects and treatment patterns in routine UK clinics, without giving any new treatment. The goa…

This study looked at 153 people with cancer who were tested for COVID-19. Researchers wanted to understand how the infection affects cancer patients and how well antibody and antigen tests work for them. The goal was to learn more to help doctors manage COVID-19 in cancer patient…