New combo therapy shows promise in controlling advanced lung cancer

NCT ID NCT02587455

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tested whether combining the immunotherapy drug pembrolizumab with standard palliative radiation is safe for people with advanced lung cancer. Twenty-four participants received different doses of pembrolizumab alongside radiation, then continued pembrolizumab alone. The main goal was to find the safest dose combination and see how well it controls cancer growth.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma thoracic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NIHR Biomedical Research Centre at RM and ICR (https://www.cancerbrc.org/)

    London, SW3 6JJ, United Kingdom

  • NIHR Biomedical Research Centre at RM and ICR (https://www.cancerbrc.org/)

    Sutton, SM2 5PT, United Kingdom