Philipps University Marburg

This study tests a new way of caring for people with new-onset stable chest pain and suspected coronary artery disease. Instead of using a standard invasive heart catheterization, the new model uses a CT scan of the heart, which is less burdensome. The study will include about 3,…

This study tests two new group therapies for adults with major depression. One therapy helps change rigid negative expectations, while the other boosts sensitivity to positive experiences. 150 participants will be randomly assigned to one of the therapies or a waiting list, and t…

This study tests a two-week smartphone program designed to help people who struggle to feel pleasure (anhedonia) and also have high depression, anxiety, or stress. Participants do three short audio-guided exercises each day, focusing on gratitude, savoring positive moments, and f…

This study tests whether adding a guided imagery exercise after a virtual reality (VR) public speaking session helps people feel less anxious in new speaking situations. 48 adults with high public speaking fear will do one VR speech, then either mentally rehearse it or use imager…

This study tests whether adding a positive mental rehearsal after exposure therapy helps people with social anxiety feel better faster. Forty participants with high social anxiety will complete a one-session exposure exercise, then either standard or positive mental rehearsal. Re…

This study tests an online mental exercise for people with social anxiety. Participants learn about anxiety and then either imagine approaching a feared social situation or do a verbal reasoning task. The goal is to see if imagining positive outcomes increases motivation and help…

This study tests whether enoxolone, a compound from licorice, can improve depression symptoms in 80 adults with unipolar depression. Researchers will measure biomarkers like hormone levels and blood pressure to see if they predict who responds better to enoxolone versus a placebo…