New group therapy aims to rewire depressed brains by fixing expectations and boosting rewards

NCT ID NCT07388004

Recruiting now Symptom relief Sponsor: Philipps University Marburg Source: ClinicalTrials.gov ↗

First seen Feb 04, 2026 · Last updated May 21, 2026 · Updated 12 times

Summary

This study compares two new group therapies for major depression: one that helps people change rigid negative expectations, and another that boosts sensitivity to positive experiences. 150 adults with depression will be randomly assigned to one of these therapies or a waiting list. The goal is to see if targeting these specific brain processes leads to better symptom relief and lasting improvement.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Philipps-University Marburg
RECRUITING

Marburg, Hesse, 35032, Germany

Contact Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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MAJOR DEPRESSIVE DISORDER (MDD)