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This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy, added to standard HIV care, can reduce psychological trauma and improve quality of life in people recently diagnosed with HIV. Forty adults who were diagnosed within the past month and startin…

This study looked at how the painkiller oxycodone behaves in the body when given as a nasal spray or an oral solution. Eight healthy adults took a single dose of each form on separate days. Researchers measured drug levels in the blood to understand absorption and side effects. T…

This completed Phase 1 study involved 8 healthy volunteers to compare how the body absorbs zolmitriptan when taken as a pill versus a nasal spray. Researchers measured drug levels in the blood and checked effects on heart rate and blood pressure over 24 hours. The goal was to bui…

This study compared two low-volume laxatives (PEG with ascorbate vs. sodium picosulfate with magnesium citrate) for colon cleansing before colonoscopy. Over 1,100 outpatients participated to see which laxative provides a better view of the colon, helping doctors find polyps and c…

This study looked at how naloxone (a drug that reverses opioid overdoses) behaves when given as a nasal spray or through an IV. Eight healthy volunteers took part to help researchers build a computer model that predicts how the drug reaches the brain. The goal was to improve unde…