Nasal vs. oral oxycodone: small study compares how the body handles the drug
NCT ID NCT07223450
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 1 study looked at how oxycodone moves through the body when given as a nasal spray or an oral solution. Eight healthy volunteers received a single dose of each form on separate days. The goal was to compare drug levels in the blood and any side effects, to help build better computer models of how the drug works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- oxycodone
- What this could lead to
- If successful, this could improve understanding of how nasal oxycodone works, potentially leading to better pain relief options.
- What could go wrong
- This is a very small, early-phase study in healthy people, not patients. Results may not apply to real-world pain treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital del Mar Research Institute
Barcelona, Spain
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