Ottawa Heart Institute Research Corporation

This study tests whether midodrine, a drug that raises blood pressure, can help people with heart failure and low blood pressure tolerate the standard heart medications that save lives. About 56 adults with weak hearts and low blood pressure will be randomly assigned to get midod…

This study tests whether dapagliflozin, a drug used for diabetes, can improve quality of life in people with long COVID. About 192 adults with persistent symptoms after a COVID-19 infection will receive either the drug or a placebo for 12 months. The main goal is to see if the dr…

This study looks for ways to predict if pericarditis (inflammation of the sac around the heart) will come back. Researchers will use special scans and blood tests in 44 adults who have already had pericarditis more than once. The goal is to help doctors identify high-risk patient…

This study looks at whether making a small opening between the upper heart chambers during mitral valve surgery can prevent heart failure symptoms after the operation. It will enroll 50 adults with severe mitral regurgitation who are already scheduled for surgery. Half will get t…

This study looks at how menopause and poor sleep affect the heart in women with type 2 diabetes. Researchers will track 381 women aged 48-58 to measure changes in heart function using ultrasound. The goal is to understand these links, not to test a treatment.