Nuvation Bio Inc.

This program offers taletrectinib to adults with advanced or spreading ROS1-positive non-small cell lung cancer who cannot use approved treatments or join ongoing studies. Participants must have a ROS1 gene fusion and adequate organ function. The goal is to provide potential bene…

This study tests a drug called taletrectinib in people with advanced lung cancer that has a specific genetic change (ROS1 positive). The goal is to see if the drug can shrink tumors and how safe it is. About 217 participants will receive the drug, and researchers will measure res…

This study tests an experimental drug called AB-106 in 173 adults with advanced non-small cell lung cancer that has a specific genetic change (ROS1 fusion). The goal is to see if the drug can shrink tumors and to check for side effects. Participants must have tried other targeted…

This study tests a new drug called NUV-1511 in people with advanced solid tumors that have not responded to other treatments. The trial has two parts: first, finding a safe dose, and second, checking if the drug shrinks tumors in specific cancers like breast, prostate, pancreatic…