New hope for lung cancer: experimental drug AB-106 targets ROS1 tumors

NCT ID NCT04395677

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called AB-106 in 173 adults with advanced non-small cell lung cancer that has a specific genetic change (ROS1 fusion). The goal is to see if the drug can shrink tumors and to check for side effects. Participants receive AB-106 alone, and their response is measured by scans.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200000, China