Northwestern University
Clinical trials sponsored by Northwestern University, explained in plain language.
-
Can a single dose before surgery shield kidneys after lung transplant?
Disease control ENROLLING_BY_INVITATIONThis study tests whether giving a TNF-alpha antibody just before a lung transplant can prevent kidney damage that often happens after surgery. About 20 adults getting a lung transplant at Northwestern will take part. Researchers will check kidney function and other outcomes like …
Phase: EARLY_PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
-
New app aims to help Court-Involved teens quit pot
Disease control OngoingThis study is testing a smartphone app called TECH to help teens aged 14-18 who are involved with the court system reduce or stop using marijuana. The app provides a private online community where teens can support each other anonymously. Researchers will track how many days teen…
Phase: NA • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 26, 2026 20:01 UTC
-
New drug shows promise against rare, aggressive thyroid cancers
Disease control OngoingThis study tests a drug called vudalimab in people with advanced anaplastic or hurthle cell thyroid cancer that has spread. The drug helps the immune system attack cancer cells and may slow tumor growth. About 54 participants will receive the treatment to see if tumors shrink.
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
Could an organ rejection drug help fight brain cancer?
Disease control OngoingThis early-phase trial tests whether adding mycophenolate mofetil (a drug usually used to prevent organ rejection) to standard chemotherapy and radiation can help treat glioblastoma, an aggressive brain cancer. About 60 newly diagnosed patients will receive different doses to fin…
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
-
Cholesterol drug may block colon cancer in colitis patients
Prevention OngoingThis study tests whether atorvastatin, a widely used cholesterol medication, can reduce the risk of colon cancer in people with long-standing ulcerative colitis who carry a specific genetic mutation (P53). About 42 participants will receive either atorvastatin or a placebo, and r…
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Prevention
Last updated Apr 26, 2026 20:00 UTC
-
Alexa lends an ear: voice assistant aims to ease depression in seniors
Symptom relief OngoingThis study tests a voice-assisted program using Amazon Alexa to help older adults (65+) with depression and their caregivers. Participants use the program for goal setting, reminders, and other support over 12 weeks. Some participants also get a guide to help them use the program…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
-
New arm exercise may help stroke patients reach farther
Symptom relief OngoingThis study tests a therapy called progressive abduction loading to help people who had a stroke improve their ability to reach outward with their affected arm. About 86 participants who had a stroke within the last 90 days will receive this therapy along with standard rehab. They…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Apr 26, 2026 20:02 UTC
-
Can mindfulness and social support boost exercise in breast cancer survivors?
Symptom relief OngoingThis study looks at which parts of a mobile health program—social support or mindfulness training—best help breast cancer survivors increase their physical activity. About 304 women who finished cancer treatment within the past 5 years will use a phone app and wear an activity tr…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
-
Brain surgery mystery: how does stimulation really work?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how electrical brain stimulation affects the brain during surgeries for epilepsy or brain tumors. Researchers want to understand why this technique helps find important areas for speech and movement. About 65 adults having brain surgery will do simple tasks li…
Phase: NA • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:00 UTC