Northwestern University

This study tests whether adding hydroxychloroquine (a drug used for malaria) to standard targeted therapy can help shrink tumors in people with advanced colorectal cancer that has a specific BRAF mutation and has stopped responding to prior treatments. The trial enrolled 7 adults…

This early-stage trial tested a new drug called tomivosertib in 8 adults with acute myeloid leukemia (AML) that had come back or not responded to prior treatments. The goal was to find a safe dose and check for side effects. The study was stopped early, so results are limited.

This early-phase trial tested whether adding the targeted drug ivosidenib to standard FLAG chemotherapy could help people with a specific genetic form of acute myeloid leukemia (IDH1-mutant AML). The study aimed to find the best dose and check for side effects in patients whose c…

This study tested angiotensin II (Giapreza) as a first-line treatment for distributive shock in patients who had a heart transplant or LVAD implant. The goal was to see if it could reduce the need for other blood pressure medications. However, the trial was terminated early after…

This study aimed to see how two antipsychotic drugs, aripiprazole and ziprasidone, affect heart risk in people with schizophrenia, schizoaffective disorder, or bipolar disorder. Researchers measured blood fats and heart electrical changes in 48 adults over 12 months. The trial wa…

This study tested whether D-cycloserine, a drug that affects brain signaling, could reduce pain in people with chronic low back pain that had not responded to other treatments. About 200 adults with at least 6 months of back pain and an average pain score of 4 or higher (on a 0–1…

This study looked at whether using a lower fluid pressure (60 mmHg) during hysteroscopy, a procedure to remove fibroids, works as well as the standard pressure (80 mmHg). The goal was to see if it improves surgery time, fluid use, and surgeon's view. The study was stopped early a…

This study tested whether placing a temporary metal stent in the stomach outlet could predict if a patient with severe gastroparesis would later benefit from a permanent procedure called GPOEM. Only 8 adults with gastroparesis that didn't improve with standard treatments took par…

This study looked at whether using a mobile health platform, alone or with regular doctor visits, helps kidney stone patients follow treatment guidelines and improve their quality of life. Researchers planned to enroll 75 adults who have had kidney stones. The study was terminate…