National University Health System, Singapore

This study tests whether a personalized digital health program — using a smartphone app, wearable devices, and lifestyle coaching — can help midlife women with abdominal obesity improve their diet, physical activity, sleep, and menopausal symptoms. Participants will wear a smartw…

This pilot study tests a personalized lifestyle program called PRISM for adults with metabolic syndrome and insulin resistance. Participants follow a time-restricted eating schedule (eating all meals within an 8-hour window) and are later assigned extra lifestyle changes like phy…

This phase 2 study tests whether the drug bepirovirsen can achieve a functional cure for chronic hepatitis B in 30 adults with low virus levels. Participants receive weekly injections for 24 weeks and undergo liver biopsies to measure changes in the virus and immune response. The…

This study tests whether using two daily exchanges of a special dialysis fluid called icodextrin can better control fluid buildup and blood pressure in children on chronic peritoneal dialysis. Ten children aged 5-18 will be enrolled. The goal is to see if this approach improves f…