National Cancer Centre, Singapore

This study tested a combination of Y90 radioembolization (a targeted radiation treatment for the liver) and nivolumab (an immunotherapy drug) in 40 Asian patients with advanced liver cancer that could not be surgically removed. The goal was to see if the combination could shrink …

This study tested a new drug called PRL3-ZUMAB in 14 people with advanced solid tumors (like stomach or liver cancer) that stopped responding to standard treatments. The drug was given every two weeks to see if it could shrink tumors or stop them from growing. Researchers also lo…

This study tested whether giving the immunotherapy drug pembrolizumab (Keytruda) along with chemotherapy before surgery can help shrink colorectal tumors and improve immune response. Thirty-three patients with non-metastatic colorectal cancer received the drugs, then had surgery.…

This early-phase trial tested whether the drug bexarotene (Targretin) could make chemotherapy-resistant triple-negative breast cancer cells sensitive to chemo again. Twelve women with metastatic, taxane-resistant breast cancer took bexarotene pills plus capecitabine (Xeloda) chem…

This pilot study tested a 6-month nurse coaching program called ENABLE for heart failure patients and their caregivers in Singapore. The program aims to educate, nurture, and advise patients and caregivers to improve quality of life. The study enrolled 125 participants to see if …

This study looked at 545 people with hereditary cancer syndromes and their relatives. It compared the usual method of asking patients to share testing information with family members to a new method where a registry also sends reminders. The goal was to see if the registry-aided …

This study analyzed blood samples from 50 adults with advanced ALK-positive lung cancer whose disease had stopped responding to one or two ALK inhibitors. The goal was to identify genetic changes in the cancer that cause drug resistance. By matching these changes to the right nex…

This study looked at over 1000 liver cancer patients who had surgery to remove their tumors. Researchers developed a model using tumor size, number of tumors, and a blood marker (AFP) to predict 5-year survival. They also compared outcomes between open and laparoscopic surgery, a…

This study looked at what happens when healthy adults eat 100 to 200 grams of durian every day for two weeks. Researchers measured changes in blood sugar, cholesterol, and gut bacteria. The goal was to understand how this popular fruit affects the body's microbiome and metabolism…