National Cancer Centre, Singapore

This study tested a drug called PRL3-ZUMAB in 14 adults with advanced solid tumors (including stomach and liver cancers) that had stopped responding to standard therapies. The drug was given intravenously every two weeks. The goal was to see if it could shrink tumors or stop them…

This study tested a 6-month program called ENABLE for heart failure patients and their caregivers in Singapore. The program provides education, support, and advice to help manage the condition. Researchers wanted to see if the program was easy to use and if it could improve quali…

This early study tested whether bexarotene, a drug already used for skin lymphoma, could make aggressive triple-negative breast cancer cells that stopped responding to taxane chemotherapy become sensitive again. 12 women with metastatic disease whose cancer had progressed after t…

This study looked at blood samples from 50 people with a specific type of lung cancer (ALK-positive) whose cancer had stopped responding to treatment. The goal was to find genetic changes in the blood that explain drug resistance, so doctors can choose the next treatment more eff…

This study gave 33 people with colorectal cancer the immune drug pembrolizumab before their surgery. Researchers wanted to see how the drug changed immune activity inside the tumor. The goal was to learn more about how the immune system responds, not to cure the disease.

This study looked at what happens when healthy adults eat durian every day for two weeks. Researchers checked changes in gut bacteria, blood sugar, and cholesterol levels. The goal was to learn how this fruit affects the body, not to treat any disease. 45 healthy staff volunteers…

This study looked at over 1,000 patients who had surgery for liver cancer (HCC) to better predict survival. Researchers used a 'metro ticket' approach combining tumor size, number of tumors, and a blood marker (AFP) to estimate 5-year survival. They also compared outcomes between…