National Cancer Centre, Singapore
Clinical trials sponsored by National Cancer Centre, Singapore, explained in plain language.
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Scientists try to 're-sensitize' resistant cancer cells to chemo
Disease control CompletedThis small, early-stage study tested whether a drug called bexarotene could make chemotherapy-resistant triple-negative breast cancer cells vulnerable to treatment again. Researchers gave bexarotene to 12 patients with advanced, taxane-resistant cancer, hoping it would change the…
Phase: PHASE1 • Sponsor: National Cancer Centre, Singapore • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Boosting the Body's defenses before cancer surgery
Disease control CompletedThis study tested if adding a drug called pembrolizumab to standard pre-surgery treatments could help the body's immune system fight colorectal cancer. It involved 33 patients with non-metastatic colon or rectal cancer who received the immunotherapy along with their usual chemoth…
Phase: PHASE2 • Sponsor: National Cancer Centre, Singapore • Aim: Disease control
Last updated Mar 18, 2026 14:52 UTC
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New coaching program aims to ease burden for heart failure families
Symptom relief CompletedThis study tested a 6-month coaching program designed to help heart failure patients and their family caregivers better manage the challenges of the illness. The program provided education and support to improve quality of life and coping skills. Researchers wanted to see if this…
Phase: NA • Sponsor: National Cancer Centre, Singapore • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Scientists feed volunteers durian to unlock gut health secrets
Knowledge-focused CompletedThis study looked at how eating durian fruit affects the gut bacteria and health markers of 45 healthy adults. Participants ate a specific amount of durian daily for two weeks while following a low-fiber diet. Researchers collected stool and blood samples to see if durian changed…
Phase: NA • Sponsor: National Cancer Centre, Singapore • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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New tool predicts liver cancer surgery survival odds
Knowledge-focused CompletedThis study analyzed data from 1,043 patients who had surgery for liver cancer between 2000 and 2018. Researchers created a prediction tool to estimate 5-year survival chances based on tumor size, number, and blood test results. The study also compared outcomes between open and la…
Sponsor: National Cancer Centre, Singapore • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:29 UTC