Blood test may unlock secrets of drug resistance in lung cancer
NCT ID NCT04087473
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study analyzed blood samples from 50 adults with advanced ALK-positive lung cancer whose disease had stopped responding to one or two ALK inhibitors. The goal was to identify genetic changes in the cancer that cause drug resistance. By matching these changes to the right next treatment, doctors hope to improve outcomes for patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors choose the right targeted therapy for patients whose lung cancer has stopped responding to current ALK inhibitors.
- What could go wrong
- This is a small, completed observational study (50 people) that looked at blood samples, not a treatment trial. The findings may not apply to all patients or lead to immediate changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asan Medical Centre
Seoul, 05505, South Korea
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National Cancer Center Singapore
Singapore, 169690, Singapore
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Seoul National University Hospital
Seoul, South Korea
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The Chinese University of Hong Kong
Hong Kong, Hong Kong
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University Malaya Medical Centre
Kuala Lumpur, Malaysia
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